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Pyridine 吡啶

规格: 99%, SpcDry,with molecular sieves, Water≤50 ppm (by K.F.), SpcSeal

CAS: 110-86-1

产品编号: H98094

MDL: MFCD00011732

品牌: INFI

Chemical Name	Pyridine
CAS Number	110-86-1
PubChem Substance ID	1049
EC Number	203-809-9
Beilstein Registry Number	103233
MDL Number	MFCD00011732
Reaxys-RN	103233
Merck Number	7970
Synonym	Pyridine {LY} Pyridine {} {LY} Pyridine {} {} {LY} Pyridine {} {} {} {LY} Pyridine {} {} {} {} {LY} Pyridine {} {} {} {} {} {LY} Pyridine {} {} {} {} {} {} {LY} Pyridine {} {} {} {} {} {} {} {LY} Pyridine {} {} {} {} {} {} {} {} {LY} Pyridine {} {} {} {} {} {} {} {} {} {LY} Pyridine {} {} {} {} {} {} {} {} {} {} {LY} Pyridine {} {} {} {} {} {} {} {} {} {} {} {LY} Pyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Pyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Pyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Pyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Pyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Pyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Pyridine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
Chemical Name Translation	吡啶
InChIKey	JUJWROOIHBZHMG-UHFFFAOYSA-N
Wiswesser Line Notation	T6NJ
LabNetwork Molecule ID	LN00163048
InChI	InChI=1S/C5H5N/c1-2-4-6-5-3-1/h1-5H
Canonical SMILES	C1=NC=CC=C1

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 360 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   PLRCAT Pharmacological Research Communications.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1969-  Volume(issue)/page/year:
   5,341,1973

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 28500 mg/m3/1H
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - lacrimation
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets.  (1810
   Frontage Rd., Northbrook, IL 60062)  Volume(issue)/page/year: 14-4/1970

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 870 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,695,1948

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 866 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Infor

{ha

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 6 mmol/L/2H
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   39,4152,1979

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 10900 ppm
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 163,23,1986

WGK Germany	2
Hazard Codes	3
Hazard statements
H225 Highly flammable liquid and vapour 高度易燃液体和蒸气 H315 Causes skin irritation 会刺激皮肤 H319 Causes serious eye irritation 严重刺激眼睛 H302+H312+H332 H332 Harmful if inhaled 吸入有害 H312 Harmful in contact with skin 皮肤接触有害 H302 Harmful if swallowed 吞食有害
RTECS	UR8400000
Precautionary statements
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。 P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。 P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。 P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。 P305+P351+P338 P308+P311 P370+P378 P403+P235 P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word	Danger
Personal Protective Equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Safety Statements
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见； S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗； S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
Risk Statements
R11 Highly flammable 非常易燃 R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害 R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性 R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性 R52 Harmful to aquatic organisms 对水生生物有害
UN Number	1282
Packing Group	II
Storage condition	2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
Hazard Class	3
Warnings	危化品目录(2015)
Restrict	危险品

溶剂，有机合成。检定和测定锑、砷、铝、铋、镉、铈、氯酸盐、铬酸盐、氰酸盐、铬、钴、铜、氰化物、金、重铬酸盐、卤素、镧、铅、锂、锰、汞、锗、镍、高氯酸盐、过硫酸盐、铂、磷、铼、镨、硅、银、硫、铊、碲、硫氰酸盐、钍、硫代硫酸盐、钛、铀、钒、锌、锆。水分测定，菌种诱变剂。酰化反应的溶剂。催化剂。

{uni_hamburg}

{ALD} Merck:14,7970

Beilstein:20(3/4)2205

{ALF} Reacts with thionyl chloride to give N-(4-pyridyl)pyridinium chloride hydrochloride, a useful intermediate for the preparation of 4-substituted pyridines by nucleophilic displacement. Thus, reaction with sulfite ion gives the sulfonate: Org. Synth. Coll., 5, 977 (1973). Similarly, pyridine can be activated to substitution at the 4-position by reaction with Ethyl chloroformate, L06311, or tert-Butyldimethylsilyl trifluoromethanesulfonate, A12174. The acyl or silyl pyridinium salt then reacts with Grignards or organocuprates, to give 4-substituted dihydropyridines which can readily be rearomatized: Bull. Chem. Soc. Jpn., 57, 1994 (1984).

{uni_hamburg} Short: II/14a

{ALD} Merck:14,7970

{ALF} For use in Cr(VI) oxidation reactions, see Chromium(VI) oxide, 12522.

{ALF} Widely used as a base and nucleophilic catalyst in acylations, sulfonylations, etc. See also 4-(Dimethylamino)pyridine, A13016.

化学属性

Mol. Formula	C5H5N
Mol. Weight	79.10
Refractive index	1.5080 to 1.5120
Boiling Point	115-116
Density	0.978
Melting Point	-42
Flash Point	20°C
TSCA	Yes
Solubility	溶于水、醇、醚等多数有机溶剂。
Autoignition Point	899 °F
Vapor Density	2.72 (vs air)
Vapor Pressure	10 mmHg ( 13.2 °C)
Stability	对光敏感，对湿度敏感
Danger-Level	甲类

*以上化合物性质及应用等信息仅供参考

电子化学品

催化剂

配体

有机硅

元素分类

其他精细新材料

Pyridine 吡啶

规格: 99%, SpcDry,with molecular sieves, Water≤50 ppm (by K.F.), SpcSeal

化学属性

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