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Trimethyltin chloride 三甲基氯化锡

规格: 1.0 M solution in THF, SpcSeal
CAS: 1066-45-1
产品编号: H93795
MDL: MFCD00000520
品牌: INFI
Chemical NameTrimethyltin Chloride
Synonym CHLOROTRIMETHYLSTANNANE CHLOROTRIMETHYLTIN Chlorotrimethylstannane Chlorotrimethyltin Chlortrimethylstannan Chlortrimethylzinn M&T chemicals 1222-45 M&T Chemicals 1222-45 OXADIXYL PESTANAL, 100 MG Stannylium, trimethyl-, chloride TRIMETHYLCHLOROTIN TRIMETHYLTIN CHLORIDE, 1.0M SOLUTION IN TETRAHYDROFURAN Tin(1+), trimethyl-, chloride Trimethylchlorostannane Trimethylstannyl chloride Trimethyltin chloride {uni_hamburg} Trimethyltin monochloride Trimethylzinnchlorid ai3-28454 chlorotrimethyl-stannan m&tchemicals1222-45; rimethyltin monochloride trimethylstannylchloride
CAS Number1066-45-1
EC Number213-917-8
Beilstein Registry Number3535111
MDL NumberMFCD00000520
PubChem Substance ID14016
Reaxys-RN3535111
Chemical Name Translation三甲基氯化锡
Wiswesser Line NotationG-SN-1&1&1
LabNetwork Molecule IDLN01301468
InChIInChI=1S/3CH3.ClH.Sn/h3*1H3;1H;/q;;;;+1/p-1
Canonical SMILESC[Sn](C)(Cl)C
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 12600 ug/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - excitement
   Behavioral - aggression
REFERENCE :
   AJPAA4 American Journal of Pathology.  (Lippincott/Harper, Journal
   Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740)  V.1-    1925-
   Volume(issue)/page/year: 97,59,1979

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - gerbil
DOSE/DURATION           : 3 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - tremor
REFERENCE :
   JJATDK JAT, Journal of Applied Toxicology.  (John Wiley & Sons Ltd., Baffins
   Lane, Chichester, W. Sussex PO19 1UD, UK)  V.1-    1981-
   Volume(issue)/page/year: 4,12,1984

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 3 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - aggression
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   JJATDK JAT, Journal of Applied Toxicology.  (John Wiley & Sons Ltd., Baffins
   Lane, Chichester, W. Sussex PO19 1UD, UK)  V.1-    1981-
   Volume(issue)/page/year: 4,12,1984

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 3 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
REFERENCE :
   JJATDK JAT, Journal of Applied Toxicology.  (John Wiley & Sons Ltd., Baffins
   Lane, Chichester, W. Sussex PO19 1UD, UK)  V.1-    1981-
   Volume(issue)/page/year: 4,12,1984

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE

TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 100 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 245,33,1990

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - rabbit Cells - not otherwise specified
DOSE/DURATION           : 10 ug/L
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 16,229,1985

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 500 ug/disk
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 280,195,1992

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 3 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 246,109,1991

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 100 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 282,61,1992

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 9 mg/kg
SEX/DURATION            : female 12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 29(2),50A,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5 mg/kg
SEX/DURATION            : female 12 day(s)

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 9 mg/kg
SEX/DURATION            : female 17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - live birth index (measured after birth)
   Reproductive - Effects on Newborn - weaning or lactation index (e.g., #
   alive at weaning per # alive at day 4)
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 29(2),50A,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 9066 ug/kg
SEX/DURATION            : female 14 day(s) pre-mating  - 21 day(s) post-birth
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - behavioral
REFERENCE :
   NTOTDY Neurobehavioral Toxicology and Teratology.  (Fayetteville, NY) V.3-8,
   1981-86.  For publisher information, see NETEEC. Volume(issue)/page/year:
   4,539,1982

Signal word Danger
WGK Germany2
Safety Statements
  • S000916
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S35 This material and its container must be disposed of in a safe way 该物料及其容器必须以安全方式处置;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S62 If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label where possible 吞食后不要催吐:立即求医并出示该容器或标签;
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
    Risk Statements
    • R11 Highly flammable 非常易燃
    • R19 May form explosive peroxides 可能生成易爆的过氧化物质
    • R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有剧毒
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
    • R38 Irritating to skin 刺激皮肤
    • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
    • R48/20
    • R48/23/25
    • R50/53
    • R62 Possible risk of impaired fertility 有削弱生殖能力的危险
    • R65 Harmful: may cause lung damage if swallowed 若吞咽可能伤害肺部器官
    • R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
      Precautionary statements
      • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
      • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
      • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
      • P273 Avoid release to the environment. 避免释放到环境中。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
      • P301+P310
      • P302+P350
      • P302+P352+P310
      • P304+P340+P310
      • P305+P351+P338
      • P337+P313
      • P370+P378
      • P403+P235
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        Hazard statements
        • H300+H310+H330
        • H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
        • H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
        • H335 May cause respiratory irritation 可能导致呼吸道刺激
        • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
        • H319 Causes serious eye irritation 严重刺激眼睛
        • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
        • H372 Causes damage to organs through prolonged or repeated exposure 长期或频繁接触会损伤器官
        • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
        • H315 Causes skin irritation 会刺激皮肤
        • H335+H336
        • H330 Fatal if inhaled 吸入致命
        • H310 Fatal in contact with skin 皮肤接触致命
        • H300 Fatal if swallowed 吞食致命
        • H331 Toxic if inhaled 吸入中毒
        • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
        • H351 Suspected of causing cancer 怀疑致癌
        • H300+H310
          Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
          RTECSWH6850000
          Packing GroupII
          UN Number 1992 3146
          Storage condition Moisture Sensitive 对湿度敏感 Poison room 0-10°C 0-10 储存温度2-8℃; 充氩保存
          Hazard Codes 3 6.1 F,T+,N T+,N,F
          Hazard Class6.1
          Restrict 剧毒
        • An organometallic compound for proteomics research
        • {uni_hamburg} Short: II/25C
        • {uni_hamburg} Short: III/20a
        • {ALD} Beilstein: 4,II,1011
        • 1066-45-1 H93795 Trimethyltin chloride
三甲基氯化锡

          化学属性

          Mol. FormulaC3H9ClSn
          Mol. Weight199.27
          Density0.968
          Melting Point37-39
          Flash Point1.4 °F
          TSCAYes
          Boiling Point156°C(lit.)
          Stability对湿度敏感

          *以上化合物性质及应用等信息仅供参考