DoMole-安徽敦茂科技

Tributylphosphine 三丁基膦

规格: 98%，SpcSeal

CAS: 998-40-3

产品编号: H88825

MDL: MFCD00009462

品牌: INFI

Chemical Name	Tri-n-Butylphosphine
MDL Number	MFCD00009462
CAS Number	998-40-3
Synonym	(n-C4H9)3P CYTOP(R) 340 P(n-Bu)3, TBP, Tris(trimethylsilyl)phosphane P(n-Bu)3, Tris(trimethylsilyl)phosphane PHOSPHINE, TRIBUTYL PHOSPHORUS TRI-N-BUTYL TBP TBUP TRI-N-BUTYLPHOSPHINE TRIBUTYL PHOSPHINE (CYTOP 340) CYTEC QUALITY TRIBUTYLPHOSPHINE Tri-n-butylphosphine Tri-n-butylphosphine,95% Tri-n-butylphosphine,99% Tri-n-butylphosphine,99%(10wt%inhexane) Tri-n-butylphosphine,min.93% Tributylfosfin Tributylphosphine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Beilstein Registry Number	4(2)971
PubChem Substance ID	13831
EC Number	213-651-2
Chemical Name Translation	三正丁基膦
Reaxys-RN	1738261
LabNetwork Molecule ID	LN00225102
InChI	InChI=1S/C12H27P/c1-4-7-10-13(11-8-5-2)12-9-6-3/h4-12H2,1-3H3

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,600,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,600,1969

WGK Germany	3
Hazard statements
H226 Flammable liquid and vapour 易燃液体和蒸气 H250 Catches fire spontaneously if exposed to air 暴露于空气自发着火 H251 Self-heating: may catch fire 自我放热：可能着火 H302 Harmful if swallowed 吞食有害 H312 Harmful in contact with skin 皮肤接触有害 H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤 H318 Causes serious eye damage 严重伤害眼睛 H335 May cause respiratory irritation 可能导致呼吸道刺激 H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害 H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
Personal Protective Equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECS	SZ3270000
Precautionary statements
P201 Obtain special instructions before use. 使用前获取专门指示。 P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。 P222 Do not allow contact with air. 不要与空气接触。 P231 Handle under inert gas. 在惰性气体中操作。 P233 Keep container tightly closed. ?保持容器密闭。 P235 Keep cool. 保持凉爽。 P235+P410 P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。 P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。 P242 Use only non-sparking tools. 只能使用无火花工具。 P243 Take precautionary measures against static discharge. 采取预防措施，防止静电放电。 P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。 P264+P265 P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。 P273 Avoid release to the environment. 避免释放到环境中。 P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。 P301+P312 P301+P317 P301+P330+P331 P301+P330+P331+P310 P302+P334 P302+P335+P334 P302+P352 P302+P361+P354 P303+P361+P353 P304+P340 P304+P340+P310 P305+P351+P338 P305+P351+P338+P310 P305+P354+P338 P308+P313 P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。 P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。 P316 P317 P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。 P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。 P330 Rinse mouth. 漱口 P362+P364 P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。 P370+P378 P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。 P403+P235 P405 Store locked up. 上锁保管。 P407 Maintain air gap between stacks/pallets. 在堆叠/货板间保持气隙。 P410 Protect from sunlight. 防止阳光照射。 P413 Store bulk masses greater than … kg/…lbs at temperatures not exceeding … oC/…oF. 商店散装超过…kg/…lbs 时温度不应超过…oC/…oF. P420 Store away from other materials. 远离其他材料。 P422 Store contents under… 存储目录在…之下。 P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word
Packing Group	I
UN Number	UN3254 3254
Risk Statements
R51/53 R22 Harmful if swallowed 吞咽有害 R17 Spontaneously flammable in air 在空气中能够自燃 R34 Causes burns 会导致灼伤 R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害 R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性 R21/22 Harmful in contact with skin and if swallowed 皮肤接触和不慎吞咽有害 R11 Highly flammable 非常易燃 R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
Safety Statements
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）； S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见； S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护； S17 Keep away from combustible material 远离可燃物料； S7 Keep container tightly closed 保存在严格密闭容器中； S43 In case of fire use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add -?Never use water) 着火时使用（指明具体的消防器材种类，如果用水增加危险，注明“禁止用水”
Storage condition	干燥，密封。 Air & Moisture Sensitive 充氩保存 2-8°C
Hazard Codes	T F,C Xi,F,C
Hazard Class	4.2

Usually used as catalyst for Domino reactions of activated conjugated dienes with β,γ?unsaturated-α-ketoesters, [3+2]-Cycloadditions,Umpolung addition reactions,Reductive carbonylation, Allylation reactions.

{ALF} A useful alternative to Triphenylphosphine, L02502 in many applications. Advantages include its greater reactivity and the water-solubility of the by-product phosphine oxide, simplifying its removal.

{ALF} Can behave as a hypernucleophilic catalyst in acylation reactions, with similar results to 4-(Dimethylamino)pyridine, A13016: J. Am. Chem. Soc., 115, 3358 (1993).

{ALF} In combination with phenyl isocyanate and a Pd catalyst, converts cinnamyl alcohol directly to a phosphorane, which reacts with aldehydes to give conjugated dienes: Chem. Lett., 1449 (1988):

{ALF} Effective catalyst for the Baylis-Hillman reaction with less tendency than the usual DABCO (1,4-Diazabicyclo[2.2.2]octane, A14003) to promote aldol type side reactions: J. Org. Chem., 62, 1521 (1997).

{ALF} For example of its use in Mitsunobu-type reactions, see Diisopropyl azodicarboxylate, L10386.

{ALD} Beilstein:4(2)971

化学属性

Mol. Formula	C12H27P
Mol. Weight	202
Refractive index	1.4590 to 1.4640
Autoignition Point	392 °F
Vapor Density	9 (vs air)
Boiling Point	110-115°C/10-12 mm
Density	0.817
Flash Point	99°F
Solubility	Insoluble in water. Miscible with ether, methanol, ethanol and benzene
TSCA	Yes
Melting Point	-65
Appearance	colorless liq. colorless to light yellow liq.
Stability	对空气和湿度敏感
Danger-Level	乙类

*以上化合物性质及应用等信息仅供参考

电子化学品

催化剂

配体

有机硅

元素分类

其他精细新材料

Tributylphosphine 三丁基膦

规格: 98%，SpcSeal

化学属性

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