• QQ: 1811068585
  • Hotline: +86 13275595566

Bromotrimethylsilane 三甲基溴硅烷

规格: 98%
CAS: 2857-97-8
产品编号: H74371
MDL: MFCD00000048
品牌: INFI
Chemical NameBromotrimethylsilane
CAS Number2857-97-8
EC Number220-672-0
Beilstein Registry Number1731135
MDL NumberMFCD00000048
Reaxys-RN1731135
PubChem Substance ID76113
Synonym 3,3'',5,5-TETRAMETHYLBENZIDINESULFATE(TMB-S) BROMOTRIMETHYLSILANE BROMOTRIMETHYLSILANE , STABILIZED WITH COPPER POWDER OR SILVER WIRE Bromotrimethylsilane {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChem} trimethylsilyl bromide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {PubChe
Chemical Name Translation三甲基溴硅烷
InChIKeyIYYIVELXUANFED-UHFFFAOYSA-N
LabNetwork Molecule IDLN00223161
InChIInChI=1S/C3H9BrSi/c1-5(2,3)4/h1-3H3
Canonical SMILESC[Si](C)(Br)C
GHS Symbol
Signal word Danger
WGK Germany3
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S8 Keep container dry 保持容器干燥;
    Risk Statements
    • R10 Flammable 易燃
    • R11 Highly flammable 非常易燃
    • R14 Reacts violently with water 遇水会猛烈反应
    • R29 Contact with water liberates toxic gas. 遇水释放出有毒气体
    • R34 Causes burns 会导致灼伤
      Precautionary statements
      • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
      • P233 Keep container tightly closed. ?保持容器密闭。
      • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
      • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
      • P241+P242+P243
      • P242 Use only non-sparking tools. 只能使用无火花工具。
      • P243 Take precautionary measures against static discharge. 采取预防措施,防止静电放电。
      • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P264+P265
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P301+P330+P331
      • P301+P330+P331+P310
      • P302+P361+P354
      • P303+P361+P353
      • P303+P361+P353+P310+P363
      • P304+P340
      • P304+P340+P310
      • P305+P351+P338
      • P305+P351+P338+P310
      • P305+P354+P338
      • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
      • P316
      • P317
      • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
      • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
      • P370+P378
      • P403+P235
      • P405 Store locked up. 上锁保管。
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        UN Number 2920
        Hazard statements
        • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
        • H226 Flammable liquid and vapour 易燃液体和蒸气
        • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
        • H318 Causes serious eye damage 严重伤害眼睛
          Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
          Hazard Codes 8 C
          Packing GroupII
          Storage condition +4°C 2-8°C 4℃ Moisture Sensitive 极易吸潮,密封避光干燥保存。
          Hazard Class8/3
        • 三重要的合成试剂,比三甲基氯硅烷反应活性高,会使二烷基磷酸酯裂解而产生各种膦酸。可用于阿地福韦的合成以及用于多肽合成的去保护
        • {ALF} Acetals, including MOM and THP ethers are readily cleaved, as are trityl and TBDMS ethers: Tetrahedron Lett., 25, 2515 (1984). Methyl glycosides are converted to the glycosyl bromides: Tetrahedron Lett., 22, 513 (1981).
        • {ALD} Beilstein: 4,IV,4008
        • {ALF} Compare also Iodotrimethyl­silane, A12902.
        • {ALF} Converts alcohols to alkyl bromides: Tetrahedron Lett., 4483 (1978), and acyl chlorides to acyl bromides: Synthesis, 216 (1981).
        • {ALF} Effective catalyst for Michaelis-Arbuzov rearrangement of trivalent organophosphorus P-O-R compounds to the corresponding P=O derivatives: Org. Lett., 5, 1661 (2003).
        • {ALF} Epoxides, oxetanes and THF are cleaved by the reagent: Synthesis, 383 (1981), as are small ring lactones: Angew. Chem. Int. Ed., 18, 689 (1979). The cleavage of acyclic ethers and esters is markedly catalyzed by IBr: J. Org. Chem., 48, 1678 (1983).
        • {ALF} In combination with DMSO and Et3N, effects the bromolactonization of unsaturated acids: J. Chem. Soc., Perkin 1, 847 (1994).
        • {SA} J. Chem. Soc., Perkin Trans. II , 263, (1991)
        • {uni_hamburg} Short: II/14a
        • {uni_hamburg} Short: II/25C
        • {ALF} Silylating agent; see Appendix 4. About 104x more reactive than TMSCl in the conversion of ketones to their silyl enol ethers in the presence of Et3N: Liebigs Ann. Chem., 1718 (1980).
        • {SA} Tetrahedron Lett. 34 , 7713, (1993)
        • 2857-97-8 H74371 Bromotrimethylsilane	三甲基溴硅烷

          化学属性

          Mol. FormulaC3H9BrSi
          Mol. Weight153.09
          Density1.14
          Refractive index1.4220 to 1.4270
          Boiling Point79 °C
          Flash Point25 °C
          TSCAYes
          Melting Point-43
          Solubility分解
          Stability对光线敏感,对湿度敏感
          Appearance 无色液体。 密度 1.16 ,熔点 -43°C ,沸点 79°C ,折射率 1.42-1.425,闪点 32°C,水溶性 DECOMPOSES 。溶于苯、乙醚、四氯乙烯,具强烈刺激味,在空气中冒白烟,具有腐蚀性,遇水分解。
          pH:A

          *以上化合物性质及应用等信息仅供参考