DoMole-安徽敦茂科技

β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate 还原型 β-烟酰胺腺嘌呤二核苷酸 2′-磷酸四钠盐水合物

规格: 95%

CAS: 2646-71-1

产品编号: H68340

MDL: MFCD00036263

品牌: INFI

Chemical Name	NADPH tetrasodium salt
Synonym	2'-NADPH 2′-NADPH 水合物 Beta-NADPH Tetrasodium Salt Hydrate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} b-NADPH Tetrasodium Salt Hydrate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {SNA} Triphosphopyridine nucleotide reduced 四钠盐 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {SNA} TPNH2 Na4 {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} NADPH (tetrasodium salt) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
MDL Number	MFCD00036263
PubChem Substance ID	87576448
CAS Number	2646-71-1
EC Number	220-163-3
Merck Number	6348
Beilstein Registry Number	2384789
Chemical Name Translation	还原型辅酶II
InChIKey	WYWWVJHQDVCHKF-ITGWJZMWSA-J
LabNetwork Molecule ID	LN00196844
Canonical SMILES	NC1=C2C(N([C@H]3[C@H](OP(O[Na])(O[Na])=O)[C@H](O)[C@@H](COP(OP(OC[C@@H]4[C@@H](O)[C@@H](O)[C@H](N5C=C(C(N)=O)CC=C5)O4)(O[Na])=O)(O[Na])=O)O3)C=N2)=NC=N1

GHS Symbol

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany	3
Storage condition	-20°C -20°C, stored under nitrogen -20℃保存 <0°C <;0 储存温度-20℃
Signal word	Warning
Safety Statements
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见； S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
Risk Statements
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P305+P351+P338
Hazard Codes	F

通常作为电子供体，是很多氧化还原酶(包括一氧化氮合成酶)的辅酶(cofactor)。

{MCE} [2]. Ng CY, F et al. Rational design of a synthetic Entner-Doudoroff pathway for improved and controllable NADPH regeneration. Metab Eng. 2015;29:86-96.

{MCE} [3]. Ju HQ, Lin JF, et al. NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications. Signal Transduct Target Ther. 2020;5(1):231. Published 2020 Oct 7.

{MCE} [4]. Stockwell BR, et al. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. Cell. 2017;171(2):273-285.

{SA} Beil. 26 ,IV,3672

{SA} Brann D, Raz L, Wang R, et al., Estrogen signaling and neuroprotection in cerebral ischemia. J. Neuroendocrinol. 24(1) , 34-47, (2011)

{SA} Canevari L, Clark JB., Alzheimer's disease and cholesterol: the fat connection. Neurochem. Res. 32 , 739-750, (2007) 摘要

{SA} Drummond GR, Selemidis S, et al., Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat. Rev. Drug Discov. 10 , 453-471, (2011) 摘要

{SA} Fraser PA., The

2646-71-1 H68340 β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate
还原型 β-烟酰胺腺嘌呤二核苷酸 2′-磷酸四钠盐水合物

化学属性

Mol. Formula	C21 H26 N7 O17 P3 . 4 Na
Mol. Weight	833.35
Density	2.28
Solubility	易溶于水(50 mg/ml).
Stability	对热和空气敏感

*以上化合物性质及应用等信息仅供参考

电子化学品

催化剂

配体

有机硅

元素分类

其他精细新材料

β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate 还原型 β-烟酰胺腺嘌呤二核苷酸 2′-磷酸四钠盐水合物

规格: 95%

化学属性

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电子化学品

催化剂

配体

有机硅

元素分类

其他精细新材料

β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate 还原型 β-烟酰胺腺嘌呤二核苷酸 2′-磷酸 四钠盐 水合物

规格: 95%

化学属性

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β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate 还原型 β-烟酰胺腺嘌呤二核苷酸 2′-磷酸四钠盐水合物