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Hexamethyldisiloxane 六甲基二硅氧烷

规格: 99%
CAS: 107-46-0
产品编号: H65798
MDL: MFCD00008265
品牌: INFI
Chemical NameHexamethyldisiloxane
MDL NumberMFCD00008265
CAS Number107-46-0
EC Number203-492-7
Beilstein Registry Number1736258
Synonym 1,1,1,3,3,3-Hexamethyl-disiloxane Fluka AG HMDSO HMDSO 六甲基二硅氧烷 Hexamethyldisiloxane SILICONE FLUID SWS-F 221 Silane, oxybis(trimethyl- belsildm0.65 六甲基乙硅氧烷 六甲基二硅氧烷, 98+%
PubChem Substance ID87570539
Reaxys-RN1736258
Chemical Name Translation六甲基二硅氧烷
Wiswesser Line Notation1-SI-1&1&O-SI-1&1&1
LabNetwork Molecule IDLN00196011
InChIInChI=1S/C6H18OSi2/c1-8(2,3)7-9(4,5)6/h1-6H3
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4500 mg/kg
TOXIC EFFECTS :
   Details of toxic effec

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 16 mL/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis with appropriate
   anesthesia
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
   Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128)  V.1-
   1990-  Volume(issue)/page/year: 12,590,1993

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8 mL/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
   Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128)  V.1-
   1990-  Volume(issue)/page/year: 12,590,1993

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 50 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 30,332,1948

TYPE OF TEST            : LD50 - Lethal dose, 50 percent k

Signal word Danger
WGK Germany2
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
    Risk Statements
    • R11 Highly flammable 非常易燃
      Precautionary statements
      • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
      • P233 Keep container tightly closed. ?保持容器密闭。
      • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
      • P241+P242+P243
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P273 Avoid release to the environment. 避免释放到环境中。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P302+P352+P332+P313+P362+P364
      • P303+P361+P353
      • P305+P351+P338
      • P305+P351+P338+P337+P313
      • P332+P313
      • P337+P313
      • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
      • P370+P378
      • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
      • P403+
      • P403+P235
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        RTECSJM9237000
        Packing GroupII
        UN Number 1993 UN 1993 3/PG 2
        Hazard statements
        • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
        • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
        • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
          Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
          Hazard Codes 3 F,N
          Hazard Class3
          Storage condition Flammables area 充氩保存
          Warnings 危化品目录(2015)
          Restrict -
        • 用作硅油生产中的封头剂,也可用作硅氮烷原料。用于硅橡胶、药品、气相色谱固定液、分析试剂、憎水剂等。
        • {ALD} Merck: 14,10497
        • Beilstein:4(3)1859
        • {ALF} Reacts with P2O5 to give trimethylsilyl polyphosphate ('PPSE'), a milder and more convenient dehydrating agent then polyphosphoric acid. For examples, and related reagents, see Phosphorus(V)­ oxide, A13348.
        • {ALD} Merck: 14,10497
        • {ALF} Silylates primary and sec-alcohols and phenols, in the presence of p-TsOH as catalyst. If the substrate contains acid-sensitive groups, PPTS can be used: Tetrahedron Lett., 4261 (1978). See Appendix 4.
        • {ALF} In the presence of FeCl3, reacts with benzotrichlorides to give substituted benzoyl chlorides in good yields: J. Chem. Soc., Chem. Commun., 808 (1977).
        • 107-46-0 H65798 Hexamethyldisiloxane
六甲基二硅氧烷

          化学属性

          Mol. FormulaC6H18OSi2
          Mol. Weight162
          Density0.764
          Refractive index1.3760 to 1.3790
          Flash Point-2°C(lit.)
          TSCAYes
          Boiling Point101
          Melting Point-59
          Vapor Density>;1 (vs air)
          Solubility不溶于水,溶于多数有机溶剂。
          Stability对湿度敏感
          Danger-Level-
          pH-:-
          Redox-

          *以上化合物性质及应用等信息仅供参考